Methyltestosterone Tablets (also known under the trademark Andorral) – synthetic testosterone in tablets, which due to the methyl group in the alpha-17 position does not break down into the liver, but this modification makes it very toxic to the liver. Methyltestosterone is one of the oldest anabolic steroids.
* Typical Methyltestosterone (analogues) brands: Androral, Stenendiol, Testoral, Glosso-Sterandryl, Methyltestosterone, Oraviron, Hormale, Madiol, Malogen, Metandren, Oreton M, and others.
* Methyltestosterone has the chemical formula: 17-Metilandrosten-4-ol-17-on-3
* Physically Androral is: colorless crystals, poorly soluble in water.
For medical purposes Methyltestosterone is used to treat decreased testicular function (reduced production of own testosterone), as well as breast cancer in women, as the replacement of testosterone in the form of tablets for oral administration and sublingual (under the tongue), is more convenient to use.
INTERACTION WITH METHYLTESTOSTONE
Given that the drug increases libido and improves the potency in men, its use is justified on a course of drugs that reduce libido (for example, deca-dick when using nandrolone or tren-dik from trenbolone). In addition, Proviron in bodybuilding is often used in precompetitive training to increase the hardness of the muscles and give it relief. It is a favorite drug of Western movie actors for giving the appearance of muscularity, afraid to use a heavier steroid “artillery”. It is also used by female bodybuilders to give the musculature density, but their dosages should not exceed 25 mg per day for not more than four weeks to exclude the phenomenon of masculinization. Although professional bodybuilders do not adhere to these norms.
Many authors point to the use of proviron and anabolic steroids (AS) of the same receptors, which allegedly reduces the effect of the latter. This information first appeared in Dan Duchaine’s Underground Steroid Handbook II. However, elementary knowledge of pharmacokinetics allows to refute this. First, this antiestrogen rapidly breaks down in the muscles to inactive metabolites. Secondly, due to high affinity for binding proteins (SHBG), the drug can increase the concentration of free AS, which increases the effectiveness of the course.
Methyltestosterone is a relatively weak androgen and is rarely used for replacement therapy.
Interactions with levothyroxine sodium: reduces (competition) binding to plasma proteins and increases the concentration of free fraction.
ADVERSE EFFECTS OF METHYLTESTOSTERONE
Andrologal causes serious side effects: high toxicity for the liver, as well as androgenic and estrogenic (due to conversion to estrogen) side effects – gynecomastia, high blood pressure, fluid accumulation in the body, acne, prostatic hypertrophy. Methyltestosterone is not recommended for use in bodybuilding, as there are safer and more effective anabolic steroids. The drug has a weak anabolic effect.
In women: amenorrhea, symptoms of virilization, hirsutism, acne eruptions;
in men: gynecomastia and oligospermia; edema, dyspeptic phenomena, cholestatic hepatitis, hepatocellular carcinoma, hypercalcemia, increased bleeding, changes in libido, headache, anxiety, depression, generalized paresthesia, hyperlipidemia, allergic reactions.
Currently, in view of the wide range of other testosterone derivatives with less side effects, its use is unjustified. However, in view of the fact that methyltestosterone is very low in the body preparation, rapid drug cancellation is possible, for example, at the beginning of androgen therapy to assess the overall tolerability and understanding of individual reactions, and the choice of dosages.
Androral – side effects
Androral causes serious side effects: high liver toxicity, as well as androgenic and estrogenic (due to conversion to estrogens) side effects – gynecomastia, high blood pressure, fluid accumulation in the body, acne, prostate hypertrophy.
“Attention” Methyltestosterone is not recommended for use in bodybuilding, since there are more safe and effective anabolic steroids. The drug has a weak anabolic effect.